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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
GLP compliance:
no
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
In this test, the melting temperature of the test item is investigated by DSC (differential scanning calorimetry). With this method the difference in energy input into the test item and a reference material as a function of temperature is recorded, while the substance and reference material are subjected to the same temperature program. This energy is the energy necessary to establish zero temperature difference between the test item and the reference material. When the sample undergoes a transition involving a change of enthalpy, that change is indicated by an endothermic deviation (e.g. melting, boiling) from the base line of the heat flow record. As result, a thermogram is obtained in which the transition heat flow is exhibited as a function of the temperature. In this diagram, the onset of the process (e.g. decomposition, physical process) as well as the heat flow of the process are shown.
Preparation of the crucibles for the determination of the melting and boiling point: The test item was weighed into an aluminum crucible under an inert atmosphere. Four tests with about 8 – 15 mg of the test item were performed. After check-weighing, the perforated lid was attached using a crucible press. As reference crucible, an empty aluminum crucible was used.
Performance of the measurement: The determination of the melting and boiling point of the test item was performed using Differential Scanning Calorimetry (DSC). The prepared crucibles (crucible with test item and reference crucible) were placed in the DSC apparatus.
At ambient conditions, the test item is a liquid. Therefore the crucibles were cooled down from ambient temperature to -100 °C with a constant cooling rate of 0.25 K/min under an inert atmosphere. After a waiting period of 30 min at -100 °C, the temperature was increased up to 500 °C at a constant heating rate of 10 K/min.
Key result
Melting / freezing pt.:
-80 °C
Atm. press.:
1 004 hPa
Decomposition:
no
Sublimation:
no
Conclusions:
The melting point of the test item is -80 °C at 1004 hPa.
Executive summary:

A study was conducted according to OECD test guideline 103 and EU Method A.1, to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Four tests with about 10 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a liquid at ambient conditions. Therefore the crucibles were cooled down from ambient temperature to -100 °C with a constant cooling rate of 0.25 K/min under an inert atmosphere. After a waiting period of 30 min at -100 °C, the temperature was increased up to 500 °C at a constant heating rate of 10 K/min. The test item crystallized below a temperature of -80 °C at atmospheric pressure (1002 – 1006 hPa) as determined by differential scanning calorimetry.

Description of key information

The melting point of the test item is -80°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-80 °C

Additional information

A study was conducted according to OECD test guideline 103 and EU Method A.1, to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Four tests with about 10 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a liquid at ambient conditions. Therefore the crucibles were cooled down from ambient temperature to -100 °C with a constant cooling rate of 0.25 K/min under an inert atmosphere. After a waiting period of 30 min at -100 °C, the temperature was increased up to 500 °C at a constant heating rate of 10 K/min.The test item crystallized below a temperature of -80 °C at atmospheric pressure (1002 – 1006 hPa) as determined by differential scanning calorimetry.