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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
other: publication
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
The concentration of Asc16 in distilled water at 25 °C was measured by UV-VIS spectroscopy (at λ = 265 nm), using a Shimadzu UV 160-A spectrophotometer.
GLP compliance:
not specified
Specific details on test material used for the study:
Asc16 analytical grade
Water solubility:
0 other: mol/L
Conc. based on:
test mat.
Temp.:
25 °C
Remarks on result:
not measured/tested
Remarks:
pH
Conclusions:
The water solubility of ascorbyl palmitate at 25 °C was determined to be 8.1E-7 M, corresponding to 0.336 mg/L.
Executive summary:

Using a photometric analytical method, Palma et al. (2002) determined the solubility of ascorbyl palmitate in distilled water at 25 °C to be 8.1 10-7 M; this corresponds to 0.336 mg/L.

Endpoint:
water solubility
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR supporting information for available literature data
Principles of method if other than guideline:
QSAR calculation
GLP compliance:
no
Type of method:
other: QSAR calculation
Water solubility:
ca. 0.025 mg/L
Temp.:
25 °C
Remarks on result:
other: QSAR calculation
Conclusions:
Water solubility of ascorbyl palmitate at 25 °C was estimated to be 0.02469 mg/L (with a given log Kow of 6.5 and a melting point of 112 °C).
Executive summary:

Providing the log Kow of 6.5 and melting point of 112 °C, the estimation of the water solubility of ascorbyl palmitate using EpiSuite v4.11 (US EPA) resulted in a value of 0.02469 mg/L (< 1 mg/L).

Description of key information

Ascorbyl palmitate is poorly soluble in water, with a water solubility determined to be < 1 mg/L.

Key value for chemical safety assessment

Additional information