Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 Sep - 31 Oct 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubility
Water solubility:
820 g/L
Incubation duration:
>= 24 - <= 72 h
Temp.:
20 °C
pH:
4.53
Remarks on result:
other: pH reported for a 40% sample solution

Any other information on results incl. tables

Calibration

The calibration of the analytical method resulted in the following calibration curve:

R-Square: 99.8813%

Offset: -0.1313

Slope: 0.1038

Curve: 0.0006

 

 

Study results

The concentrations of the different test solutions were calculated automatically using the equation of the calibration curve. The results are summarised in the table below:

 

Incubation time

[hours]

Water solubility

[g/L]

Average

[g/L]

24

810

820±10.0

48

830

72

820

 

The water solubility of the test item at 20 °C is 820 ± 10.0 g/L (standard deviation).

The pH value of a sample solution (40%) was 4.53.

Applicant's summary and conclusion