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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

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Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC1=CCC(CC1)C(C)(C)O
Key result
Type:
BCF
Value:
67.8 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.83; log Kow used: 3.28)

The BCF of l-alpha terpineol was 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of l-alpha terpineol was 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of l-alpha terpineol was 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(C)C1(O)CCC(=CC1)C
Key result
Type:
BCF
Value:
65.8 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.82; log Kow used: 3.26)

The BCF of (+)-terpinen-4-ol was 65.8 L/kg wet-wt (log BCF from regression-based method = 1.82).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of (+)-terpinen-4-ol was 65.8 L/kg wet-wt (log BCF from regression-based method = 1.82).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of (+)-terpinen-4-ol was 65.8 L/kg wet-wt (log BCF from regression-based method = 1.82).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(C)C1(O)CCC(=CC1)C
Key result
Type:
BCF
Value:
65.8 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.82; log Kow used: 3.26)

The BCF of (-)-terpinen-4-ol was 65.8 L/kg wet-wt (log BCF from regression-based method = 1.82).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of (-)-terpinen-4-ol was 65.8 L/kg wet-wt (log BCF from regression-based method = 1.82).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of (-)-terpinen-4-ol was 65.8 L/kg wet-wt (log BCF from regression-based method = 1.82).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(C)C1=CCC(C)(O)CC1
Key result
Type:
BCF
Value:
73.3 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.87; log Kow used: 3.33)

The BCF of 3-terpinen-1-ol was 73.3 L/kg wet-wt (log BCF from regression-based method = 1.87).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of 3-terpinen-1-ol was 73.3 L/kg wet-wt (log BCF from regression-based method = 1.87).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of 3-terpinen-1-ol was 73.3 L/kg wet-wt (log BCF from regression-based method = 1.87).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: C(C(CC1C2)C1(C)C)(=C2)C
Key result
Type:
BCF
Value:
394.9 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.597; log Kow used: 4.44)

The BCF of alpha pinene was 394.9 L/kg wet-wt (log BCF from regression-based method = 2.597).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of alpha pinene was 394.9 L/kg wet-wt (log BCF from regression-based method = 2.597).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of alpha pinene was 394.9 L/kg wet-wt (log BCF from regression-based method = 2.597).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: C(=CC=C(C1)C)(C1)C(C)C
Key result
Type:
BCF
Value:
296 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.47; log Kow used: 4.25)

The BCF of alpha terpinene was 296 L/kg wet-wt (log BCF from regression-based method = 2.47).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of alpha terpinene was 296 L/kg wet-wt (log BCF from regression-based method = 2.47).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of alpha terpinene was 296 L/kg wet-wt (log BCF from regression-based method = 2.47).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC12CCC(C1)C(C)(C)C2O
Key result
Type:
BCF
Value:
57.4 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.76; log Kow used: 3.17)

The BCF of beta fenchol was 57.4 L/kg wet-wt (log BCF from regression-based method = 1.76).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of beta fenchol was 57.4 L/kg wet-wt (log BCF from regression-based method = 1.76).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of beta fenchol was 57.4 L/kg wet-wt (log BCF from regression-based method = 1.76).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(=C)C1CCC(CC1)(O)C
Key result
Type:
BCF
Value:
82.6 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.92; log Kow used: 3.41)

The BCF of beta terpineol-cis was 82.6 L/kg wet-wt (log BCF from regression-based method = 1.92).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of beta terpineol-cis was 82.6 L/kg wet-wt (log BCF from regression-based method = 1.92).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of beta terpineol-cis was 82.6 L/kg wet-wt (log BCF from regression-based method = 1.92).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(=C)C1CCC(CC1)(O)C
Key result
Type:
BCF
Value:
82.6 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.92; log Kow used: 3.41)

The BCF of beta terpineol-trans was 82.6 L/kg wet-wt (log BCF from regression-based method = 1.92).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of beta terpineol-trans was 82.6 L/kg wet-wt (log BCF from regression-based method = 1.92).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of beta terpineol-trans was 82.6 L/kg wet-wt (log BCF from regression-based method = 1.92).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(C)C12CC1C(C)C=C2
Key result
Type:
BCF
Value:
420.3 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.624; log Kow used: 4.48)

The BCF of beta thujene was 420.3 L/kg wet-wt (log BCF from regression-based method = 2.624).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of beta thujene was 420.3 L/kg wet-wt (log BCF from regression-based method = 2.624).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of beta thujene was 420.3 L/kg wet-wt (log BCF from regression-based method = 2.624).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC1(C)C2CCC1(C)C(O)C2
Key result
Type:
BCF
Value:
27.7 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.44; log Kow used: 2.69)

The BCF of borneol was 27.7 L/kg wet-wt (log BCF from regression-based method = 1.44).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of borneol was 27.7 L/kg wet-wt (log BCF from regression-based method = 1.44).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of borneol was 27.7 L/kg wet-wt (log BCF from regression-based method = 1.44).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: C(C(CC1C2)C2)(C1(C)C)=C
Key result
Type:
BCF
Value:
282.7 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.451; log Kow used: 4.22)

The BCF of camphene was 282.7 L/kg wet-wt (log BCF from regression-based method = 2.451).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of camphene was 282.7 L/kg wet-wt (log BCF from regression-based method = 2.451).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of camphene was 282.7 L/kg wet-wt (log BCF from regression-based method = 2.451).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC12CCC(CC1)C(C)(C)O2
Key result
Type:
BCF
Value:
29.8 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.47; log Kow used: 2.74)

The BCF of cineole was 29.8 L/kg wet-wt (log BCF from regression-based method = 1.47).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of cineole was 29.8 L/kg wet-wt (log BCF from regression-based method = 1.47).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of cineole was 29.8 L/kg wet-wt (log BCF from regression-based method = 1.47).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC1=CCC(CC1)C(C)(C)O
Key result
Type:
BCF
Value:
67.8 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.83; log Kow used: 3.28)

The BCF of d-alpha terpineol was 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of d-alpha terpineol was 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of d-alpha terpineol was 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: C(=CCC(C(=C)C)C1)(C1)C
Key result
Type:
BCF
Value:
360.5 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.557; log Kow used: 4.38)

The BCF of d-limonene was 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of d-limonene was 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of d-limonene was 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: COc1ccc(CC=C)cc1
Key result
Type:
BCF
Value:
90.1 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.95; log Kow used: 3.47)

The BCF of estragole was 90.1 L/kg wet-wt (log BCF from regression-based method = 1.95).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of estragole was 90.1 L/kg wet-wt (log BCF from regression-based method = 1.95).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of estragole was 90.1 L/kg wet-wt (log BCF from regression-based method = 1.95).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC1=CCC(=CC1)C(C)C
Key result
Type:
BCF
Value:
433 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.64; log Kow used: 4.50)

The BCF of gamma terpinene was 433 L/kg wet-wt (log BCF from regression-based method = 2.64).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of gamma terpinene was 433 L/kg wet-wt (log BCF from regression-based method = 2.64).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of gamma terpinene was 433 L/kg wet-wt (log BCF from regression-based method = 2.64).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(=C1CCC(C)(O)CC1)C
Key result
Type:
BCF
Value:
89.3 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.95; log Kow used: 3.46)

The BCF of gamma terpineol was 89.3 L/kg wet-wt (log BCF from regression-based method = 1.95).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of gamma terpineol was 89.3 L/kg wet-wt (log BCF from regression-based method = 1.95).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of gamma terpineol was 89.3 L/kg wet-wt (log BCF from regression-based method = 1.95).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(C)C12CCC(C)(CC1)O2
Key result
Type:
BCF
Value:
42.3 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 1.63; log Kow used: 2.97)

The BCF of isocineole was 42.3 L/kg wet-wt (log BCF from regression-based method = 1.63).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of isocineole was 42.3 L/kg wet-wt (log BCF from regression-based method = 1.63).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of isocineole was 42.3 L/kg wet-wt (log BCF from regression-based method = 1.63).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: C(=CCC(C(=C)C)C1)(C1)C
Key result
Type:
BCF
Value:
360.5 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.557; log Kow used: 4.38)

The BCF of l-limonene was 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of l-limonene was 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of l-limonene was 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: CC(C)c1ccc(C)cc1
Key result
Type:
BCF
Value:
236 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.37; log Kow used: 4.10)

The BCF of p-cymene was 236 L/kg wet-wt (log BCF from regression-based method = 2.37).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of p-cymene was 236 L/kg wet-wt (log BCF from regression-based method = 2.37).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of p-cymene was 236 L/kg wet-wt (log BCF from regression-based method = 2.37).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: C=C1C(C2)C2(C(C)C)CC1
Key result
Type:
BCF
Value:
576.8 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.761; log Kow used: 4.69)

The BCF of sabinene was 576.8 L/kg wet-wt (log BCF from regression-based method = 2.761).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of sabinene was 576.8 L/kg wet-wt (log BCF from regression-based method = 2.761).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of sabinene was 576.8 L/kg wet-wt (log BCF from regression-based method = 2.761).

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Internationally accepted method, EPI Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model.
Guideline:
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Meylan, W.M., Howard, P.H, Aronson, D., Printup, H. and S. Gouchie. 1997. "Improved Method for Estimating Bioconcentration Factor (BCF) from Octanol-Water Partition Coefficient", SRC TR-97-006 (2nd Update), July 22, 1997; prepared for: Robert S. Boethling, EPA-OPPT, Washington, DC; Contract No. 68-D5-0012; prepared by: ; Syracuse Research Corp., Environmental Science Center, 6225 Running Ridge Road, North Syracuse, NY 13212.
Meylan, W.M., Howard, P.H., Boethling, R.S. et al. 1999. Improved Method for Estimating Bioconcentration / Bioaccumulation Factor from Octanol/Water Partition Coefficient. Environ. Toxicol. Chem. 18(4): 664-672 (1999).
Specific details on test material used for the study:
SMILES: C(=C(C)C)(CCC(=C1)C)C1
Key result
Type:
BCF
Value:
413.3 L/kg
Remarks on result:
other: (Log BCF from regression-based method = 2.616; log Kow used: 4.47)

The BCF of terpinolene was 413.3 L/kg wet-wt (log BCF from regression-based method = 2.616).

Validity criteria fulfilled:
not applicable
Conclusions:
The BCF of terpinolene was 413.3 L/kg wet-wt (log BCF from regression-based method = 2.616).
Executive summary:

Using the BCFBAF v3.01 model of EPI Suite v4.11, the BCF of terpinolene was 413.3 L/kg wet-wt (log BCF from regression-based method = 2.616).

Description of key information

Weight of evidence: BCFBAF v3.01 model of EPI Suite v4.11. The bioconcentration factor (BCF) was estimated to be in the range of 28 -577 L/kg wet-wt for all main components. The BCF of the test substance has been determined to be the highest of the major components (>1%), i.e. 433 L/kg wet-wt, assuming the worst case scenario.

Key value for chemical safety assessment

BCF (aquatic species):
433 L/kg ww

Additional information

Weight of evidence: The bioconcentration factor (BCF) of the main components are available from EpiSuite calculation:

L-alpha terpineol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83)

D-alpha terpineol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 67.8 L/kg wet-wt (log BCF from regression-based method = 1.83)

Terpinolene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 413.3 L/kg wet-wt (log BCF from regression-based method = 2.616).

Gamma terpineol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 89.3 L/kg wet-wt (log BCF from regression-based method = 1.95)

Cineole: EPI-Suite, BCFBAF v3.01. The estimated BCF is 29.8 L/kg wet-wt (log BCF from regression-based method = 1.47)

Isocineole: EPI-Suite, BCFBAF v3.01. The estimated BCF is 42.3 L/kg wet-wt (log BCF from regression-based method = 1.63)

L-Limonene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557)

D-Limonene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 360.5 L/kg wet-wt (log BCF from regression-based method = 2.557)

Camphene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 282.7 L/kg wet-wt (log BCF from regression-based method = 2.451)

Alpha terpinene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 296 L/kg wet-wt (log BCF from regression-based method = 2.47)

Gamma terpinene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 433 L/kg wet-wt (log BCF from regression-based method = 2.64)

Alpha pinene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 394.9 L/kg wet-wt (log BCF from regression-based method = 2.597)

3 -terpinen-1 -ol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 73.3 L/kg wet-wt (log BCF from regression-based method = 1.87)

+/-terpinen-4 -ol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 65.8 L/kg wet-wt (log BCF from regression-based method = 1.82)

Beta fenchol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 57.4 L/kg wet-wt (log BCF from regression-based method = 1.76)

cis/trans beta terpineol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 82.6 L/kg wet-wt (log BCF from regression-based method = 1.92)

Beta thujene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 420.3 L/kg wet-wt (log BCF from regression-based method = 2.624)

Sabinene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 576.8 L/kg wet-wt (log BCF from regression-based method = 2.761)

Paracymene: EPI-Suite, BCFBAF v3.01. The estimated BCF is 236 L/kg wet-wt (log BCF from regression-based method = 2.37)

Estragole: EPI-Suite, BCFBAF v3.01. The estimated BCF is 90.1 L/kg wet-wt (log BCF from regression-based method = 1.95)

Borneol: EPI-Suite, BCFBAF v3.01. The estimated BCF is 27.7 L/kg wet-wt (log BCF from regression-based method = 1.44)

Based on the composition of the substance and a weight of evidence approach, the bioconcentration factor (BCF) is determined to be 433 L/kg.