Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Version / remarks:
17 Jul 1992
Deviations:
no
Remarks:
Minor deviations (background bottles and aeration) without adverse effects on study integrity.
Qualifier:
according to guideline
Guideline:
EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
Version / remarks:
30 May 2008
Deviations:
no
Remarks:
Minor deviations (background bottles and aeration) without adverse effects on study integrity.
Qualifier:
according to guideline
Guideline:
other: ISO International Standard 9439 "Water Quality - Evaluation of ultimate aerobic biodegradability of organic compounds in aqueous medium - carbon dioxide evolution test"
Version / remarks:
1999
Deviations:
no
Remarks:
Minor deviations (background bottles and aeration) without adverse effects on study integrity.
Qualifier:
according to guideline
Guideline:
other: ISO International Standard 10634 "Water Quality - Guidance for the preparation and treatment of poorly water-soluble organic compounds for the subsequent evaluation of their biodegradability in an aqueous medium"
Version / remarks:
1995
Deviations:
no
Remarks:
Minor deviations (background bottles and aeration) without adverse effects on study integrity.
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
3-[2-({[4-methanesulfonyl-2-(trifluoromethyl)phenyl]methyl}amino)pyridin-3-yl]prop-2-yn-1-ol
Cas Number:
2092997-91-4
Molecular formula:
not applicable
IUPAC Name:
3-[2-({[4-methanesulfonyl-2-(trifluoromethyl)phenyl]methyl}amino)pyridin-3-yl]prop-2-yn-1-ol

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic, non-adapted
Duration of test (contact time):
28 d
Initial test substance concentrationopen allclose all
Initial conc.:
22.5 mg/L
Based on:
test mat.
Initial conc.:
12 mg/L
Based on:
TOC
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
CO2 evolution

Results and discussion

% Degradationopen allclose all
Parameter:
% degradation (CO2 evolution)
Value:
4
Sampling time:
28 d
Remarks on result:
other: bottle A
Parameter:
% degradation (CO2 evolution)
Value:
10
Sampling time:
28 d
Remarks on result:
other: bottle B

Applicant's summary and conclusion

Interpretation of results:
not readily biodegradable