Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2015-05-20 to 2015-07-03
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: inhouse data

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid: viscous
Details on test material:
Stabilized EMIM BF4:
assay EMIM+ (HPLC): 93.36 wt%
assay stabilizer (HPLC): 4.89 wt%
assay BF4- (titration): 86.68 wt%

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
Pow
Partition coefficient:
0.012
Temp.:
25 °C
pH:
6.05

Any other information on results incl. tables

Summary of the results, mean and standard deviation of eachn-octanol / water ratio, overall mean and standard deviation:

 

ratio

 

 

 

n-octanol : water

Pow

log Pow

1a

1:1

0,01163

-1,93431

1b

1:1

0,01169

-1,93226

 

mean

0,01166

-1,93329

 

standard deviation

0,00004

0,00145

 

 

 

 

2a

2:1

0,01176

-1,92945

2b

2:1

0,01161

-1,93498

 

mean

0,01169

-1,93222

 

standard deviation

0,00011

0,00391

 

 

 

 

3a

1:2

0,01191

-1,92405

3b

1:2

0,01161

-1,93535

 

mean

0,01176

-1,92970

 

standard deviation

0,00022

0,00799

 

 

 

 

 

overall mean

0,01170

-1,93173

 

overall standard deviation

0,00012

0,00435

Applicant's summary and conclusion

Conclusions:
A partition coefficient of 0,01170 (log Pow = -1,93173) at 25°C has been determined for the test compound stabilized EMIM BF4, pointing to a hydrophilic behavior of the chemical substance. The pH value of each aqueous phase is 6,05.