Registration Dossier

Administrative data

Endpoint:
relative self-ignition temperature (solids)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: non-GLP guideline study, but test procedure well documented

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.16 (Relative Self-Ignition Temperature for Solids)
Deviations:
yes
Remarks:
see 'Principles of method if other than guideline'
Principles of method if other than guideline:
As a melting range had been determined as 235 – 242 °C under decomposition, the oven was only heated to 250 °C for the determination of self-ignition temperature and not up to 400 °C.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): (1R)-1-[(4R,4aR,8aS)-2,6-bis(4-chlorophenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
- Expiration date of the lot/batch: December 2012
- Storage condition of test material: Room Temperature: (20 ± 5°C); Keep away from humidity

Results and discussion

Relative self-ignition temperature (solids)
Remarks on result:
no self-ignition observed up to the melting point

Applicant's summary and conclusion

Conclusions:
Self-heating of the substance up to 400°C can be excluded: The substance melts in the range of 235 - 242 °C under decomposition, no self-heating has been observed in this study up to 250°C.