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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other: bibliography
Adequacy of study:
weight of evidence
Study period:
2008
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data considered reliable by ECHA.

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2008

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
The flavor and Fragance High Production Volume Consortia; Revised Robust Summaries for Bictclic Terpene Hydrocarbons Submitted to EPA under the HPV Challange Programm. p. 140 (Novembre9,20016) Available from, as of October 8, 2008
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Pin-2(3)-ene
EC Number:
201-291-9
EC Name:
Pin-2(3)-ene
Cas Number:
80-56-8
Molecular formula:
C10H16
IUPAC Name:
2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
Test material form:
liquid

Administration / exposure

Details on oral exposure:
Ten male Wistar. The DL50 calculated from data was 3700 mg/kg bw (95% C.L. 2300-5100 mg/kg bw)

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
3 700 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 5 based on GHS criteria
Conclusions:
The acute oral LD50 value in rats was reported 3700 mg/kg. The substance is classified category 5 on GHS regulation.