Registration Dossier
Registration Dossier
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EC number: 202-354-3 | CAS number: 94-68-8
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- other: secondary literature
- Title:
- NITE - Chemical Management Field - GHS Information GHS Classification Result
- Year:
- 2 011
- Bibliographic source:
- GHS-J [Internet]. National Institute of Technology and Evaluation (NITE): GHS Classification Results by the Japanese Government. Available from: http://www.echemportal.org
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- not specified
- Test type:
- other: not specified
Test material
- Specific details on test material used for the study:
- not specified
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Details on inhalation exposure:
- not specified
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 7 h
- Remarks on duration:
- not specified
- Concentrations:
- not specified
- No. of animals per sex per dose:
- not specified
- Control animals:
- not specified
- Details on study design:
- not specified
- Statistics:
- not specified
Results and discussion
- Preliminary study:
- not specified
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 0.955 mg/L air
- Exp. duration:
- 4 h
- Mortality:
- not observed
- Clinical signs:
- other: not specified
- Body weight:
- not specified
- Gross pathology:
- not specified
- Other findings:
- not specified
Any other information on results incl. tables
not specified
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- Besides, the s aturated vapour pressure concentration (0.722 mg/L) (converted to a 4-hour equivalent: 0.955 mg/L) exposure to rats for 7 hours resulted in no deaths, but the category could not be determined only from this data
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