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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

No study investigating the toxicity of D-Glucopyranose, oligomeric, C10-16-alkyl glycosides, carboxymethyl ethers, sodium salts (CAS 383178-66-3) to terrestrial organisms is available. Thus, an analogue substance (D-Glucopyranose, oligomeric, C10-16-alkyl glycosides, CAS 110615-47-9) is used in a read across approach to assess the toxicity of the target substance to macroarthropoden and plants. The read across is based on structural similarity between the target substance and the supporting substance. The target substance is a derivative of the supporting substance, where a carboxymethy group is added to a -OH function. All other structural elements (alkyl side chain, glycoside moiety) are identical. The additional carboxymethyl group renders the substance more hydrophilic, which usually decreases aquatic toxicity. This is confirmed by the acute ecotox data of the target substance (TS) and the supporting substance (SS): Fish: 7.1 mg/L (TS) vs 3.0 mg/L (SS); Invertebrates: 172 mg/L (TS) vs 7.0 mg/L (SS). Therefore, read across from D-Glucopyranose, oligomeric, C10-16-alkyl glycosides to D-Glucopyranose, oligomeric, C10-16-alkyl glycosides, carboxymethyl ethers, sodium salt is fully justified as this is considered to be a worst case approach.

In a 14 days acute toxicity test Eisenia foetida was exposed to the analogue substance according to OECD guideline 207 (Hüls 1992). No adverse effects were detected. Thus, the EC50 of Eisenia foetida in artificial soil was determined to be higher than 1000 mg/kg soil.

The effects of D-Glucopyranose, oligomeric, C10-16-alkyl glycosides (CAS: 110615-47-9) to terrestrial plants were evaluated in the “Terrestrial plants, growth test” (Seedling emergence test) according to the OECD guideline 208. Seed from oat (Avena sativa), turnip (Brassica rapa) and tomato (Lycopersicon esculentum) were used for the test (Steber et al. 1995). After the test duration of 14 days no adverse effects on the germination of the seed were observed in the highest test concentration of 654 mg/kg. In addition to these results the substance is “readily biodegradable” and has no potential to adsorb to soil (log Koc: 1.7).

Based on these results the analogue substance is not considered to be harmful to terrestrial organisms. Due to the structural similarity as mentioned above this conclusion can also be drawn for the substance to be registered.