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Physical & Chemical properties

Melting point / freezing point

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Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From September 14, 2017 to February 14, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
not specified
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
not specified
GLP compliance:
yes
Type of method:
capillary method
Key result
Decomposition:
yes
Decomp. temp.:
ca. 106 °C
Remarks on result:
not determinable

Results:

Decomposition: 106°C

Comments

Suspected decomposition was observed from 106°C (the sample started rising up the tube with the evolution of colourless gas). At 130°C the sample ejected out of the tube. The test was terminated.

Conclusions:
Under the study conditions, melting point of the test substance could not be determined due to decomposition.

Executive summary:

A study was conducted to determine the melting point of the test substance, using capillary method with photocell detection according to OECD Guideline 102 and EU Method A.1, in compliance with GLP. During the study, suspected decomposition was observed from 106°C (the sample started rising up the tube with the evolution of colourless gas). At 130°C the sample ejected out of the tube. As a result further testing was stopped. Under the study conditions, melting point of the test substance could not be determined due to decomposition (Chilworth, 2018).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From September 14, 2017 to February 14, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
not specified
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
not specified
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Key result
Decomposition:
yes
Decomp. temp.:
ca. 120 °C
Remarks on result:
not determinable

Results:

Table 1: Table of results (Screening Test)

 

Endotherm onset temp. (°C)

Heat of melting (J.g-1)

Exotherm onset temp. (°C)

Heat of decomposition

(J.g-1)

Screening Test

42.18

293.01

197.81

122.54

 

Table 2: Table of results

 

Run B

Run C

Run D

Run E

Endotherm onset temp. (°C)

N/A

N/A

N/A

N/A

Mass of Sample Used (g)

4.37

4.91

4.35

3.59

Start Temperature (°C)

0

0

0

0

Final Temperature (°C)

170

170

170

170

Scan Rate (K/min)

1

1

1

1

 

Comment

Suspected decomposition endotherms observed around 120°C. Brown residues were observed in the sample pans after the tests. A visual analysis was performed to confirm suspicion of decomposition.

Conclusions:
Under the study conditions, the melting point for the test substance could not be determined due to decomposition.
Executive summary:

A study was conducted to determine the melting point of the test substance, using Differential Scanning Calorimetry (DSC), according to OECD Guideline 102 and EU Method A.1, in compliance with GLP. Under the study conditions, the melting point for the test substance could not be determined due to decomposition (Chilworth, 2018).

Description of key information

Melting point of the test substance was determined using the differential scanning calorimetery (DSC) and capillary method, according to OECD Guideline 102 and EU Method A.1 (Chilworth, 2018).

Key value for chemical safety assessment

Additional information

No melting point could be determined due to decomposition (at 120°C (DSC method) or at 106°C (Capillary method)).