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EC number: 947-760-8 | CAS number: -
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 October 2016 to 12 November 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 2-ethylhexyl 12-hydroxyoctadecanoate
- EC Number:
- 249-793-7
- EC Name:
- 2-ethylhexyl 12-hydroxyoctadecanoate
- Cas Number:
- 29710-25-6
- Molecular formula:
- C26H52O3
- IUPAC Name:
- 2-ethylhexyl 12-hydroxyoctadecanoate
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Remarks on result:
- other: The partition coefficient of the test item has been determined to be 3.63 x 10^9 to >1.0 x 10^10, log10 Pow 9.56 to >10.0.
- Details on results:
- Preliminary Estimate: The estimated log10 Pow for the representative structure of the test item was calculated to be from 10.06
Definitive Test: The partition coefficient of the test item has been determined to be 3.63 x 10^9 to >1.0 x 10^10. Overall log10 Pow was 9.56 to >10.0.
Applicant's summary and conclusion
- Conclusions:
- The Partition Coefficient (n-octanol/water) was 3.63 X 10^9 to >1.0 X 10^10, log10 Pow 9.56 to >10.0.
- Executive summary:
The Partition Coefficient (n-octanol/water) was 3.63 X 10^9 to >1.0 x 10^10, log10 Pow 9.56 to >10.0, using the HPLC method, designed to be compatible with Method A.8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 117 of the OECD Guidelines for Testing of Chemicals, 13 April 2004.
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