Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
Deviations:
yes
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-one
EC Number:
604-446-2
Cas Number:
144850-45-3
Molecular formula:
C14H16O3
IUPAC Name:
1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-one
Test material form:
solid: particulate/powder

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
100 mg/L
Based on:
not specified
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
O2 consumption
Reference substance
Reference substance:
benzoic acid, sodium salt

Results and discussion

Test performance:
All the validity criteria were successfull exept the biodegradability in the toxicity control. Therefore, the test item was inhibitory at the testes concentration of 100 mg/L.
% Degradation
Key result
Parameter:
% degradation (O2 consumption)
Value:
0
Sampling time:
28 d
Details on results:
Based on ThODNH4, the 10-day window failed and the degradation rate of the test item D305 is zero fater 28 days of incubation.

BOD5 / COD results

BOD5 / COD
Key result
Parameter:
ThOD
Value:
0 g O2/g test mat.
Results with reference substance:
% biodegradation with reference item is >68 afater 28 days of incubation

Applicant's summary and conclusion

Validity criteria fulfilled:
no
Interpretation of results:
not readily biodegradable
Conclusions:
Based on ThODNH4, the 10-day window failed and the degradation rate of the test item D305 is zero fater 28 days of incubation.
Executive summary:

Biodegradability was performed according OECD 301F guideline. Based on ThODNH4, the 10-day window failed and the degradation rate of the test item D305 is zero fater 28 days of incubation.