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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
unsuitable test system

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1981
Report date:
1981

Materials and methods

Principles of method if other than guideline:
according to Smyth, H.F. et al.: Am. Ind. Hyg. Ass. J. 23, 95-107 (1962)
GLP compliance:
no
Test type:
other: inhalation hazard test

Test material

Constituent 1
Chemical structure
Reference substance name:
2-piperidinoethanol
EC Number:
221-244-6
EC Name:
2-piperidinoethanol
Cas Number:
3040-44-6
Molecular formula:
C7H15NO
IUPAC Name:
2-piperidinoethanol
Details on test material:
Name of the test substance used in the study report: 1-(2-hydroxyethyl)-piperidin

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
air
Details on inhalation exposure:
Inhalation of an atmosphere enriched with vapours of the test substance. For the enrichment 200 L air per hour were conducted through a 5 cm thick layer of the test substance.
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
7 h
Concentrations:
not specified
No. of animals per sex per dose:
12
Control animals:
yes

Results and discussion

Effect levels
Remarks on result:
not determinable because of methodological limitations
Mortality:
None
Clinical signs:
other: Lagophthalmos, snout wiping, nasal secretion, ruffled fur.
Gross pathology:
Nothing abnormal detected.

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification