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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Both source (1-(3-(Dimethylamino)propyl)urea (CAS 31506-43-1, EC 401-950-2) )and target 1,3-bis[3-(dimethylamino)propyl]urea (CAS  52338-87-1, EC 257-861-2) substances are based on the reaction product of dimethylaminopropylamine (DMAPA) and urea.  

The main product of this reaction is the singly-substituted urea product, (3-(dimethylamino)propyl) urea (or mono-DMAPAU)

However, an unavoidable side-reaction is the formation of the doubly-substituted product, 1,3-bis[3-(dimethylamino)propyl]urea, which is formed by the disproportionation of mono-DMAPAU.

The test item contains approximately 15% of 1,3-bis[3-(dimethylamino)propyl]urea.

Read-across is also claimed based on structural similarity and properties of both reaction products. Justification attached.

Key value for chemical safety assessment

BMF in fish (dimensionless):
2.3

Additional information