Registration Dossier

Administrative data

First-aid measures

After inhalation: If inhaled, take the victim into fresh air. In case of respiratory arrest, apply artificial breathing.
After skin contact: Wash off with soap and plenty of water.
After eye contact: Rinse eyes with water as a precaution.
After swallowing: Never instil anything in the mouth of an unconscious person. Rinse mouth with water.

Fire-fighting measures

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry extinguishing agent or carbon dioxide.
Special hazards arising from the substance or mixture: Carbon oxides, hydrogen bromide
Firefighting instructions: In case of fire, wear self-contained breathing apparatus if necessary.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:
Avoid dust formation. Do not inhale fumes/mist/gas.

Personal protective equipment
Eye/Face Protection: For eye protection, only use equipment that has been tested and approved according to official standards such as NIOSH (US) or EN 166 (EU).
Skin protection: Work with gloves. Gloves must be examined before use. Use a suitable extraction method (without touching the outer glove surface) to avoid skin contact with this product. Disposal of contaminated gloves after use in accordance with legal regulations and good laboratory practice. Washing and drying hands. The protective gloves to be used must meet the specifications of EC Directive 89/686/EEC and the resulting standard EN 374.
full contact
Material: nitrile rubber
Minimum layer thickness: 0.4 mm
Breakthrough time: 480 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, size M)
splash contact
Material: nitrile rubber
Minimum layer thickness: 0.11 mm
Breakthrough time: 120 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, size M)
When dissolving in or mixing with other substances and under conditions deviating from EN 374, you must contact the supplier of CE-approved gloves. This recommendation is considered as advice and must be evaluated by an occupational hygienist and a safety expert who knows the specific situation of the intended use of our customers. It should not be understood as consent for any specific use.
Body protection: Select body protection according to its type, concentration and quantity of dangerous substances and according to the respective workplace.
Respiratory protection: Respiratory protection is not required. Where protection against harmful dust concentrations is required, use a dust mask type N95 (US) or a respirator with filter type P1 (EN 143). Respiratory protective devices and components must be tested and approved according to appropriate government standards such as NIOHS (US) or CEN (EU).

Methods and materials for retention and cleaning: Sweep up and shovel up. For disposal, place in suitable and closed containers.

Handling and storage

Protective measures for safe handling: In case of dust formation, ensure suitable ventilation.
Conditions for safe storage taking into account incompatibilities: Store in a cool place. Container tightly closed in a dry, well-ventilated place
and keep it in a safe place.

Transport information

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Marine transport (IMDG)

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Exposure controls / personal protection

Normal operation
Workers use PPE as a good practice to minimise possible exposures from minor accidental leaks during loading and unloading the reaction vessel, even though rigorous containment is ensured through technical means. Procedures are in place for disposal or cleaning of contaminated PPE.

Accident and incidents
A fully trained Emergency Response Team (ERT) is in place to react in case of accidents and incidents resulting in unexpected releases of the intermediate in order to minimize risks of exposures to humans and the environment. Components of the ERT are selected among senior site operators and technicians and are periodically trained and certified to respond to emergencies. Trainings and certifications of members ERT are subject to periodical revisions and approval by Local Fire Department. PPE as specified in emergency procedures and training are required in case of accidents and incidents. Procedures are in place for disposal or cleaning of contaminated PPE, as appropriate.

Maintenance and cleaning
Workers use additional PPE for cleaning the reaction vessel. A short exposure may occur during a maintenance operation, involving opening of a section of the pipeline connecting the reactor with loading station due to accidental presence of a residue of diluted intermediate that may lead to skin exposure. As a result, workers are given a specific work instruction on how to open this section, and are required to use high-efficiency PPE for skin and respiratory protection, as a precautionary and protective measure during all maintenance work, where there is a potential for exposure. PPE type is specified in the permit-to-work documents. Procedures are in place for disposal or cleaning of contaminated PPE, as appropriate.

Stability and reactivity

Disposal considerations