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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

EC3= 5.08% This value is predicted by a QSAR Model.

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
skin sensitisation, other
skin sensitisation in vivo (LLNA) (From QSAR prediction)
Type of information:
Adequacy of study:
key study
Study period:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
other: REACH Guidance on QSARs R.6
Specific details on test material used for the study:
SMILES: OCC{P-}(O)C{P-}(O)C{P+}(O)C{P-}(O)C(=O)O{-}.[Cu]{+}
Key result
Interpretation of results:
Category 1B (indication of skin sensitising potential) based on GHS criteria
Toxicity of the target chemical (5.08 %) is predicted by QSAR "Modelo QSAR 180409 Sensitisation LLNA E3 Gluconato".
In conclusion, EC3 value > 2 %; based on GHS criteria the substance has skin sensitising potential (Skin Sens 1B).
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

The value obtained for Skin Sensitsation of the prediction value (EC3) was 5.08%. According to GHS criteria, EC3 value > 2 % , the substance must be classified as a skin sensitiser 1B.