Registration Dossier
Registration Dossier
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EC number: 609-091-7 | CAS number: 35202-54-1
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Technical Guidance Document EUR 20268 Determination of Particle Size Distribution
- Version / remarks:
- The determination was carried out using a procedure designed to be compatible with that given in European Commission Guidance Document EUR 20268 ‘Determination of Particle Size Distribution, Fibre Length and Diameter Distribution of Chemical Substances’ (2002).
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- determination of fibre length and diameter distributions
- Type of particle tested:
- other: powder
- Type of distribution:
- mass based distribution
Test material
- Reference substance name:
- 3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
- EC Number:
- 609-091-7
- Cas Number:
- 35202-54-1
- Molecular formula:
- C11H11NO2
- IUPAC Name:
- 3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
Constituent 1
Results and discussion
- Mass median aerodynamic diameter:
- >= 10 - < 100 µm
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- <= 10 µm
- Distribution:
- >= 50 %
- No.:
- #2
- Size:
- 0 - < 100 µm
- Distribution:
- ca. 7.2 %
Applicant's summary and conclusion
- Conclusions:
- The percentage of test item having an inhalable particle size of less than 100 μm was determined to be 7.2%.
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