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EC number: 212-506-0 | CAS number: 822-89-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 June 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- Hydroxyl-2-pyridone
- EC Number:
- 212-506-0
- EC Name:
- Hydroxyl-2-pyridone
- Cas Number:
- 822-89-9
- Molecular formula:
- C5H5NO2
- IUPAC Name:
- 1-hydroxy-1,2-dihydropyridin-2-one
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: A0103550
- Analytical purity: 98.9%
- Expiration date: 01 October 2003
- Storage condition: at room temperature in the dark
Results and discussion
Melting / freezing point
- Key result
- Melting / freezing pt.:
- ca. 148 °C
- Atm. press.:
- 1 013.25 hPa
- Decomposition:
- yes
- Decomp. temp.:
- ca. 210 °C
- Remarks on result:
- other: A brown molten residue remained after the tests, indicating reaction and/or decomposition.
- Remarks:
- Probably due to a small amount of impurities, the melting process started already between 120°C and 133°C.
Any other information on results incl. tables
The DSC curve with a heating rate of 20°C/min (first experiment) showed an endothermic peak between 120°C and 163°C. The extrapolated onset temperature of the peak was 149°C. The effect was most likely obtained due to melting. A small exothermic peak was observed starting at 227°C due to reaction and/or decomposition of the test item. After the experiment, a brown molten residue remained (original colour: beige). The sample had lost 6% of its mass. To investigate the melting peak, repeated heating cycles were applied with a heating rate of 10°C/min. The extrapolated onset temperature of the melting peak was 148°C during Experiment 2 and 3 (both runs). After Experiment 2, the sample appeared to have been molten, but no change of colour was observed. During the 1st run and 2nd run of the 3rd Experiment, a very small endothermic peak was observed around 182°C and 210°C respetively, probably caused by reaction or decomposition of the test substance. After the experiment, the sample appeared to have been molten and had a brown colour.
The melting temperature of the test substance was determined as the average melting temperature obtained from Experiment 1, 2 and 3 and equals 148°C (421 K). Probably due to a small amount of impurities, the melting process started already between 120°C and 133°C.
Applicant's summary and conclusion
- Conclusions:
- The melting temperature of the test substance was determined at 148°C (421 K) by using DSC.
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