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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 to 28 November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Remarks on result:
not determinable
Conclusions:
During the preliminary estimation stage, estimated octanol solubility was determined to be < 26.25 mg/L. The estimated water solubility was found to be < 0.13 mg/L. These are below the LOD of the analytical method therefore the formal solubility analysis could not be performed.

Description of key information

During the preliminary estimation stage, estimated octanol solubility was determined to be < 26.25 mg/L. The estimated water solubility was found to be < 0.13 mg/L. These are below the LOD of the analytical method therefore the formal solubility analysis could not be performed.

Key value for chemical safety assessment

Additional information