Registration Dossier

Administrative data

Description of key information

LD50 (oral) 2500 mg/kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
Reference
Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Reference:
Composition 0
Qualifier:
no guideline required
Principles of method if other than guideline:
Handbook value
GLP compliance:
not specified
Test type:
fixed dose procedure
Limit test:
no
Test material information:
Composition 1
Species:
rabbit
Strain:
not specified
Sex:
male/female
Route of administration:
oral: gavage
Vehicle:
water
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
ca. 2 500 mg/kg bw
Based on:
test mat.
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
2 500 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

The available data for the substance indicate no potential for acute toxicity via oral route. No classification is warranted for acute toxicity according to CLP Regulation 1272/2008.