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Ecotoxicological information

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Analysis after hydrolysis revealed several products: tetrafluoroborate anion, dodecyl ethyl sulfide, and three glutaconate diesters (dimethyl glutaconate, methyl pentyl glutaconate, and dipentyl glutaconate in approximately a 1:2:1 molar ratio).  Because of the differential solubilities of the hydrolysis products and formation of an oily phase, it was determined that the aquatic toxicity tests could not be conducted on the parent material as the insoluble materials could not be removed while maintaining a consistent series of exposures.  Test data on the hydrolysis products was collected instead.  Dodecyl ethyl sulfide is not commercially available.  Dodecyl methyl sulfide was substituted as the closest available surrogate. Similarly, methyl pentyl glutaconate is not commercially available, and a 1:1 molar mixture of dimethyl glutaconate and dipentyl glutaconate was tested instead. Toxicity was observed in a test of the 1:1 glutaconate mixture on Pseudokirchneriella subcapitata, although the other hydrolysis products (or surrogate chemical) had 72-h EC10 and EC50 values >100 mg/L. An additivity model was used to estimate the toxicity of methyl pentyl glutaconate and ultimately MTDID 47403. The most conservative calculation resulted in an EC50 of 1.3 mg/L on MTDID 47403 basis.  Results from short-term toxicity tests on Daphnia magna with the hydrolysis products of MTDID 47403 (or surrogate) all indicate that the 48-hour EC50 is > 100 mg/L. Details on short-term toxicity testing results for these hydrolysis products follow in subsequent sections.

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