Registration Dossier
Registration Dossier
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EC number: 209-060-4 | CAS number: 554-12-1
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- not specified
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- Fragrance raw materials monographs - Methyl propionate
- Author:
- Opdyke, D.L.J & Letizia, C.
- Year:
- 1 982
- Bibliographic source:
- Food and Chemical Toxicology V20 1982 p765
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Publication data does not specify the method.
Reference to orignal publication: Moreno, O.M. (1977) Report to RIFM, 7 October - GLP compliance:
- not specified
- Test type:
- other: Not specified
Test material
- Reference substance name:
- Methyl propionate
- EC Number:
- 209-060-4
- EC Name:
- Methyl propionate
- Cas Number:
- 554-12-1
- Molecular formula:
- C4H8O2
- IUPAC Name:
- methyl propanoate
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- According to information in secondary literature, the acute dermal LD50 of the substance to the rabbit is in excess of 5000 mg/kg.
- Executive summary:
According to information in secondary literature, the acute dermal LD50 of the substance to the rabbit is in excess of 5000 mg/kg.
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