Registration Dossier

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
not specified
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Valid with restrictions. This is peer reviewed data where the test methodology and identity of the substance have been evaluated, and a reliable and representative value for the endpoint has been selected. No information on GLP status or test guideline followed is available.

Data source

Reference
Reference Type:
review article or handbook
Title:
Sax’s Dangerous Properties of Industrial Materials, 11th Edition, Volume 3
Author:
Lewis Sr., R.J.
Year:
2004
Bibliographic source:
Sax’s Dangerous Properties of Industrial Materials, 11th Edition, Volume 3

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Handbook data does not specify the method. Data from peer reviewed source.
GLP compliance:
not specified
Test type:
other: Handbook data does not specify the method. Data from peer reviewed source.

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LC50
Effect level:
27 other: g/m³
Based on:
not specified
Remarks on result:
other: exposure duration not specified

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
According to handbook data the acute inhalation LC50 of the substance to mice is 27 g/m³.
Executive summary:

According to handbook data the acute inhalation LC50 of the substance to mice is 27 g/m³.