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EC number: 701-255-7 | CAS number: -
Body weight data are presented in the table below:
Initial body weight
Final body weight
The purpose of this study was to determine the potential irritant and/or corrosive effects of the test article on eyes of rabbits.
The test article, Daltolac XR 159, was administered (0.1 ml) into the conjunctival sac of the right eye of three New Zealand White rabbits. Upon instillation, the eye was held closed for approximately 1 second to prevent loss of material. The left eye of each animal served as an untreated control. Both eyes of all animals were examined and scored for ocular irritation prior to dose and at 1, 24, 48 and 72 hours post-dose and on Day 5.
In the animals receiving Daltolac XR 159, iritis was observed in one of three rabbits at 1 hour post treatment. Scores for conjuctival redness, chemosis and/or discharge were observed at 1, 24, 48 and/or 72 hour post-dose. There was no irritation present on Day 5 and the in-life study was terminated.
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