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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Justification for type of information:
2-ethylhexanol and pentane-2,4-dione are two main hydrolysis prodcuts of the target substance. Properties of the the two substance are used for read-across.
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
not specified
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
freshwater
Total exposure duration:
48 h
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 48 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mobility
Validity criteria fulfilled:
yes
Conclusions:
The 48h EC50 was 48 mg/l tested on Daphnia magna.

Description of key information

Static, freshwater on Daphnia magnia. Similar to OECD method 202.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
39 mg/L

Additional information

No studies were conducted on the target substance, Reaction product of Titanium tetrakis(2-ethylhexan-1-olato) and pentane-2,4-dione. As the target substance hydrolyses rapidly (half-life < 30 minutes) the intrinsic properties are related to hydrolysis products of the target substance.

On the basis that if entering the environmental, this substance will quickly dissociate to form the inorganic (poorly soluble) titanium dioxide and two well-evaluated organic substances – 2-ethylhexanol and pentane-2,4-dione. .

The titanium dioxide is not considered further in this report as aquatic toxicity assessments do not apply.

One study on pentane-2,4-dione tested on Daphnia magna indicated EC50 (48h) was 48 mg/l (Thurston et al. 1985). For 2-ethylhexanol, the reported 48h EC50 was 39 mg/l (ECHA,https://echa.europa.eu/information-on-chemicals).

Based on the findings, the lowest value of EC50 from 2-ethylhexanol, 39 mg/l, was chosen for CSA.