Registration Dossier

Administrative data

Description of key information

- Acute toxicity: oral: LD50 = 91 mg/kg bw for rat (female), LD50 = 402 mg/kg bw for rat (male)

- Acute toxicity: inhalation: LC50 = 338 mg/m³ (4h) for rat (female)

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
91 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LC50
338 mg/m³

Additional information

Justification for classification or non-classification

- Acute toxicity: oral

Based on the LD50 of 91 mg/kg bw for female rats (oral route) a classification as category 3 / H301 is warranted.

- Acute toxicity: inhalation

Based on the LC50 of 0.338 mg/L per 4h inhalation of dust a classification as category 2 / H330 is warranted.

Furthermore, based on a pronounced irritation potential of the substance on the respiratory tract a classification as STOT SE category 3 / H335 (lung, inhalation) is warranted.