Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23 May 2016 - 02 May 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
Physical appearance: white crystalline powder
Test item storage: In refrigerator (2-8°C)
Specific details on test material used for the study:
Decomposition temp.: 300°C
Melting temp.: 155.1°C

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test item)

Temperature [°C]

Weight loss [µg/min]

νT

[g/cm2/h]

log νT

log PT

PT[Pa]

 

120

 

1.76047

 

2.10×10-4

 

-3.68

 

0.02

 

1.1

 

 

1.63367

 

1.95×10-4

 

-3.71

 

-0.02

 

0.95

 

130

3.77716

4.51×10-4

-3.35

0.47

2.9

 

 

4.06057

 

4.85×10-4

 

-3.31

 

0.51

 

3.2

 

140

7.89436

9.42×10-4

-3.03

0.90

7.9

 

 

7.30748

 

8.72×10-4

 

-3.06

 

0.85

 

7.1

 

150

18.0688

2.16×10-3

-2.67

1.38

24

 

 

16.3065

 

1.95×10-3

 

-2.71

 

1.32

 

21

 

 

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C was determined to be 4.0E-7 Pa.
The vapour pressure of the substance at 25°C was determined to be 1.1E-6 Pa.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

The constants specific for the experimental arrangement were determined using a set of 5 reference compounds. A vapour pressure curve for the test item was constructed from duplicate measurements at 120°C, 130°C, 140°C and 150°C. The vapour pressure of the substance at 20°C and 25°C was determined by extrapolation to be 4.0E-7 Pa and 1.1E-6 Pa, resp.