GAMMA-CYCLODEXTRINE, 6A,6B,6C,6D,6E,6F,6G,6H-OCTABROMO-6A,6B,6C,6D,6E,6F,6G,6H-OCTADEOXY-

Boiling point

Administrative data

Endpoint:

boiling point

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a solid which decomposes before boiling

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 01 February 2016 to 20 April 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

1998

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Decomposition:

yes

Decomp. temp.:

> 225 °C

Remarks on result:

other: No melting point.

TGA EXPERIMENT

From 100°C upwards the weight of the sample decreased significantly. At 244°C the sample weight had decreased by 25%. After the experiment, a charred residue remained in the sample container. The change of the colour indicated reaction and/or decomposition of the test item.

 

DSC EXPERIMENT 1

A small endothermic peak between 75°C and 150°C was observed. The extrapolated onset temperature of the peak could not be determined due to the peak shape. Another endothermic effect was observed between 225°C and 275°C. After the experiment, a charred residue remained in the sample container.

DSC EXPERIMENT 2

To investigate the peak between 75°C and 150°C a repeated heating cycle was applied. With the first heating the extrapolated onset temperature of the endothermic peak between 75°C and 150°C could not be determined. During cooling no exothermic peaks could be observed. Therefore, it was concluded that the endothermic effect between 75°C and 150°C was not resulting from the melting of the test item. During the second heating, the endothermic effect between 225 and 275°C did not shift to a higher temperature. It demonstrated that reaction and/or decomposition of the test item was the reason for the endothermic effect. After the experiment, a charred residue remained in the sample container.

According to these observations, it was concluded that the test item has no melting and no boiling temperature.

Conclusions:

The substance Broomdex has no melting temperature. Reaction and/or decomposition started at 225°C.

Executive summary:

The melting temperature was determined using differential scanning calorimetry in a GLP study according to EC A.1, OECD 102 and OPPTS 830.7200.

Reaction and/or decomposition started at 225°C. Melting of the test item was not observed below the temperature at which reaction and/or decomposition started. The substance has no melting temperature.