GAMMA-CYCLODEXTRINE, 6A,6B,6C,6D,6E,6F,6G,6H-OCTABROMO-6A,6B,6C,6D,6E,6F,6G,6H-OCTADEOXY-

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 01 February 2016 to 20 April 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2016

Report date:

2016

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

2008

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

1998

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

(1R,3R,5S,6R,8S,10S,11S,13R,15S,16R,18R,20S,21R,23S,25S,26S,28R,30S,31R,33S,35S,36S,38R,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-5,10,15,20,25,30,35,40-octakis(bromomethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2³,⁶.2⁸,¹¹.2¹³,¹⁶.2¹⁸,²¹.2²³,²⁶.2²⁸,³¹.2³³,³⁶]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol

EC Number:

611-044-0

Cas Number:

53784-84-2

Molecular formula:

C48H72Br8O32

IUPAC Name:

(1R,3R,5S,6R,8S,10S,11S,13R,15S,16R,18R,20S,21R,23S,25S,26S,28R,30S,31R,33S,35S,36S,38R,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-5,10,15,20,25,30,35,40-octakis(bromomethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2³,⁶.2⁸,¹¹.2¹³,¹⁶.2¹⁸,²¹.2²³,²⁶.2²⁸,³¹.2³³,³⁶]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol

Test material form:

solid: particulate/powder

Details on test material:

- Appearance: off-white powder
- Storage condition of test material: At room temperature

Results and discussion

Melting / freezing point

Key result

Decomposition:

yes

Decomp. temp.:

> 225 °C

Remarks on result:

other: No melting point.

Any other information on results incl. tables

TGA EXPERIMENT

From 100°C upwards the weight of the sample decreased significantly. At 244°C the sample weight had decreased by 25%. After the experiment, a charred residue remained in the sample container. The change of the colour indicated reaction and/or decomposition of the test item.

 

DSC EXPERIMENT 1

A small endothermic peak between 75°C and 150°C was observed. The extrapolated onset temperature of the peak could not be determined due to the peak shape. Another endothermic effect was observed between 225°C and 275°C. After the experiment, a charred residue remained in the sample container.

DSC EXPERIMENT 2

To investigate the peak between 75°C and 150°C a repeated heating cycle was applied. With the first heating the extrapolated onset temperature of the endothermic peak between 75°C and 150°C could not be determined. During cooling no exothermic peaks could be observed. Therefore, it was concluded that the endothermic effect between 75°C and 150°C was not resulting from the melting of the test item. During the second heating, the endothermic effect between 225 and 275°C did not shift to a higher temperature. It demonstrated that reaction and/or decomposition of the test item was the reason for the endothermic effect. After the experiment, a charred residue remained in the sample container.

According to these observations, it was concluded that the test item has no melting and no boiling temperature.

Applicant's summary and conclusion

Conclusions:

The substance Broomdex has no melting temperature. Reaction and/or decomposition started at 225°C.

Executive summary:

The melting temperature was determined using differential scanning calorimetry in a GLP study according to EC A.1, OECD 102 and OPPTS 830.7200.

Reaction and/or decomposition started at 225°C. Melting of the test item was not observed below the temperature at which reaction and/or decomposition started. The substance has no melting temperature.