Registration Dossier
Registration Dossier
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EC number: 238-484-2 | CAS number: 14484-64-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- yes
- Remarks:
- slight modifications, however no further specification of deviations
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Details on sampling:
- not specified
- Vehicle:
- not specified
- Details on test solutions:
- The test solution was prepared fresh each day.
- Test organisms (species):
- Poecilia reticulata
- Details on test organisms:
- not specified
- Test type:
- semi-static
- Water media type:
- freshwater
- Remarks:
- Information on chemical composition of the test media are given in Leeuwen, C:J and Maas, H. Enviromental Pollution (Series A) 37 (1985) 105-115
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- not specified
- Post exposure observation period:
- not specified
- Hardness:
- not specified
- Test temperature:
- not specified
- pH:
- not specified
- Dissolved oxygen:
- not applicable
- Salinity:
- not specified
- Conductivity:
- not specified
- Nominal and measured concentrations:
- not specified
- Details on test conditions:
- not specified
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.09 mg/L
- Nominal / measured:
- nominal
- Details on results:
- not specified
- Results with reference substance (positive control):
- not specified
- Reported statistics and error estimates:
- 95%-confidence interval reported: 0.06 - 0.18 mg/L
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- A 96-hour LC50 was determined to be 0.09 mg/L for P. reticulata. The 95% confidence interval is calculated to be 0.06 - 0.18 mg/L.
- Executive summary:
The study was carried out according to OECD Guideline 203 with slight modifications. The 96-hour LC50 was determined to be 0.09 mg/L for Poecilia reticulata. The 95 % confidence interval is calculated to be 0.06 - 0.18 mg/L.
Reference
Description of key information
LC50 (96h) = 0.09 mg/L for Poecilia reticulata (OECD Guideline 203 with slight modifications)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.09 mg/L
Additional information
The study was carried out according to OECD Guideline 203 with slight modifications. The 96-hour LC50 was determined to be 0.09 mg/L nominal for Poecilia reticulata. The 95 % confidence interval is calculated to be 0.06 - 0.18 mg/L.
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