Registration Dossier

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Ames:

One study in 2018 shows positive to tester strains TA1537, TA98, TA100 and WP2uvrA in the absence of S9-mix, and the results were reproducible in a follow up experiment, these increases are considered to be biologically relevant and the test item is considered to be mutagenic.

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (positive)

Additional information

Justification for classification or non-classification

Positive result in Ames study.

Therefore in accordance with Regulation (EC) No. 1272/2008 Table 3.5.1, this substance should be classified as a Category 2 mutagen.