Registration Dossier

Administrative data

Endpoint:
phototransformation in air
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from reliable database

Data source

Referenceopen allclose all

Title:
First rate constants for reactions of OH-radicals with amides
Author:
Koch R et al.
Year:
1997
Bibliographic source:
Int J Chem Kinetics 29: 81-87, cited in:HSDB (2007). Search results for N-Methylacetamide, CAS No. 79-16-3. Database content through Dec 2006.
Reference Type:
secondary source
Title:
No information
Author:
Meylan WM and Howard PH
Year:
1993
Bibliographic source:
Chemosphere 26: 2293-2299.||cited in:|HSDB (2007). Search results for N-Methylacetamide, CAS No. 79-16-3. Database content through Dec 2006.

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Method: other (measured)
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
TS-Freetext:
N-Methylacetamide

Study design

Estimation method (if used):
PHOTOCHEMICAL REACTION WITH OH RADICALS
- Concentration of OH radicals: 500000 molecules/cm³
- Degradation rate constant: 5.20E-12 cm³/molecule-sec at 27 °C (Koch et al., 1997)

OTHER ESTIMATION METHOD:
Details on test conditions:
Sensitiser (for indirect photolysis): OH
Sensitiser concentration: 500000 molecule/cm³
Duration of test at given test condition
Temp.:
27 °C

Results and discussion

Dissipation half-life of parent compound
DT50:
3.1 d

Any other information on results incl. tables


The rate constant for the vapor-phase reaction of N-methylacetamide with photochemically-produced hydroxyl radicals is 5.20E-12 cm³/molecule-sec at 27 °C (Koch et al., 1997).

This corresponds to an atmospheric half-life of about 3.1 days (SRC) at an atmospheric concentration of 5E05 hydroxyl radicals per cm³ (Meylan and Howard, 1993).

Rate constant (for indirect photolysis): = 0.0000000000052 cm³/(molecule*sec)
Degradation in % (for indirect photolysis): = 50 after 3.1 day(s)

Applicant's summary and conclusion