Registration Dossier
Registration Dossier
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EC number: 608-408-6 | CAS number: 29736-24-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Taking into account the Guinea pig maximisation test (in vivo) with BRUGGOLITE FF6 , the weight of evidence analysis (Read-across from structurally related substances) indicates that BLANCOLEN HP is devoid of any skin sensitation.
The skin sensitisation was tested according to OECD 406 with a 10 % solution respectively a 75:25 mixture of the test substance solution with vaseline. No skin irritation was observed, not any sensitisation reaction was registered and the skin fold thickness did not increase.
Taking into account a in-vivo-study with albino rats with BRUGGOLITE FF6 , the weight of evidence analysis (Read-across from structurally related substances) indicates that the test item is devoid of any acute dermal irritation/corrosion.
Migrated from Short description of key information:
Skin sensitisation: no skin irritation (dermal induction); no sensitisation reaction; no increase in skin fold thickness
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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