Registration Dossier
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EC number: 605-620-0 | CAS number: 171869-89-9
Endpoint summary
Administrative data
Description of key information
Additional information
Suitable experimental data testing the toxicity of 1,2-Ethanediamine, N-{3-(trimethoxysilyl)propyl}-,N-{(ethenylphenyl)methyl}derivate, hydrochlorides (CAS 171869-89-9) towards aquatic organisms were not available. Therefore, a read across from the structurally analogous substance reaction mass containing six benzylated amine silanes (EC 700-961-2) was conducted. Both substances are expected to hydrolyse within the timescale of an aquatic toxicity test. Further information on the read across approach can be found in the attached justification in the respective target entry and in the overall justification for grouping of substances attached in IUCLID Section 13.
Short- and long-term toxicity data for the source substance reaction mass containing six benzylated amine silanes (EC 700-961-2) were available for fish, aquatic invertebrates and algae.
All studies were performed according to the appropriate OECD guidelines and GLP standards. The study testing the acute toxicity of the substance towards fish resulted into an LC50 (96 h) of 75 mg/L (nominal). An EC50 (48 h) of 74 mg/L (nominal) was determined for the effects of the substance on the mobility of Daphnia magna. A study testing the effects of the substance on the growth rate of the algae Scenedesmus subspicatus resulted in an ErC50 (72 h) value of 69 mg/L and a NOErC (72 h) of 10 mg/L (nominal). A 28 d juvenile test using Oncorhynchus mykiss as the test organism revealed a NOEC of 5 mg/L (nominal) while a 21 d NOEC of 0.32 mg/L was determined for the effects of the substance on the reproduction rate of Daphnia magna.
The test item is a complex substance, which degrades quickly in water into monomeric (benzyl substituted aminoalkylsilane triols) or oligomeric (di-, tri-, or higher benzyl substituted aminoalkylsiloxanes) silicon-based substances and methanol. The tests were performed with the parent compound, which was supposed to display the principal aquatic hazard. However, since the substance hydrolyses rapidly it is assumed that the tested organisms were exposed to both the parent substance and the hydrolysis products.
Furthermore the influence of the test item reaction mass containing six benzylated amine silanes (EC 700-961-2) on the respiration rate of activated sludge was tested according to the OECD guideline 209 and GLP standards. The study resulted into an EC50 (3 h) of 569 mg/L and a NOEC (3 h) of 130 mg/L (nominal).
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