Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The Chemical Safety Assessment according to Annex I indicates that secondary poisoning is unlikely as substance and its relevant degradation products decompose rapidly and there is a low potential for bioaccumulation (Log Kow below 3). Therefore, the toxicity testing to terrestrial invertebrates is scientifically not necessary.


The short-term toxicity to terrestrial plants does not need to be conducted because the substance and its relevant degradation products decompose rapidly (study scientifically not necessary).


According to ECHA guidance Chapter R.7c: Endpoint specific guidance, Version 3.0 – June 2017, Section R.7.11.2 the following applies: "In the case of readily biodegradable substances which are not directly applied to soil it is generally assumed that the substance will not enter the terrestrial environment and as such there is no need for testing of soil organisms is required."


The substance 2-ethyl-2-oxazoline was shown to be readily biodegradable, is fully miscible in water (mobile in soil) and is unlikely to absorb to soil (log Pow 0.198). Finally, no direct application to soil is known and indirect exposure of soil is also unlikely. The substance is used for chemical syntheses and as a monomer for polymer production in industrial processes, making exposure to soil very unlikely. There are no professional nor consumer uses. Thus, long-term exposure to soil is not of concern and no testing for long-term toxicity to soil microorganisms is required, based on exposure considerations.

Additional information