Registration Dossier
Registration Dossier
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EC number: 202-417-5 | CAS number: 95-41-0
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-hexylcyclopent-2-enone
- EC Number:
- 202-417-5
- EC Name:
- 2-hexylcyclopent-2-enone
- Cas Number:
- 95-41-0
- Molecular formula:
- C11H18O
- IUPAC Name:
- 2-hexylcyclopent-2-en-1-one
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Doses:
- 5000 mg/kg bw
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 14 days
- Examinations performed: mortality, toxicity and skin irritation
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- discriminating dose
- Effect level:
- 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- One animal died on day 3
- Clinical signs:
- other: No toxicity observed
- Other findings:
- Skin irritation: Slight redness 2/10; Moderate redness 8/10; Slight edema 4/10; Moderate edema 6/10
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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