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EC number: 203-674-6 | CAS number: 109-46-6
Cumulative dead fish
Mortality at the end of the period
This study was designed to determine the effects of 1,3 -dibutylthiourea to Danio rerio over a 96h period with static conditions, according to the OECD 203 Guideline. Fish were exposed to a series of dilutions of a stock solution in dilution water (0 ; 6.25 ; 12.5 ; 25 ; 50 and 100 mg/L). The stability of the substance was confirmed over the 96h test period (i.e. deviation <20% between T0 and 96h measurements). Nominal concentrations were thus used to determine 96h-LC50 (all results are mg/L). LC50 was 17.8 mg/L.
The definitive test succeeded to meet the validity criterion detailed as follows:
- The mortality in the control did not exceed 10% at the end of the test.
- The dissolved oxygen in the test tanks remained above 60% of the air saturation value at the end of the test.
- The pH did not vary by more than 1 unit.
One OECD 203 study is available for acute toxicity of 1,3 -dibutylthiourea to fish. LC50 was 17.8 mg/L
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