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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

ethylamine--boron trifluoride is known to cause irritation of skin, eyes and the respiratory trackt

Key value for chemical safety assessment

Skin irritation / corrosion

Link to relevant study records
Reference
Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
no guideline available
Principles of method if other than guideline:
orientation test
GLP compliance:
not specified
Species:
rabbit
Strain:
not specified
Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
not specified
Duration of treatment / exposure:
not specified
Observation period:
not specified
Number of animals:
not specified
Details on study design:
not specified
Irritation parameter:
other: not specified
Basis:
other: not specified
Time point:
other: not specified
Score:
>= 1.75
Max. score:
1.75
Reversibility:
not specified
Remarks on result:
probability of weak irritation
Interpretation of results:
Category 2 (irritant) based on GHS criteria
Conclusions:
the test report concludes only slight skin irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as skin irritant irritant
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Link to relevant study records
Reference
Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
no guideline available
Principles of method if other than guideline:
orientation test
GLP compliance:
not specified
Specific details on test material used for the study:
not specified
Species:
rabbit
Strain:
not specified
Vehicle:
not specified
Amount / concentration applied:
not specified
Duration of treatment / exposure:
not specified
Observation period (in vivo):
not specified
Duration of post- treatment incubation (in vitro):
not specified
Number of animals or in vitro replicates:
not specified
Details on study design:
not specified
Irritation parameter:
other: not specified
Basis:
other: not specified
Time point:
other: not specified
Score:
>= 1.4
Max. score:
1.4
Reversibility:
not specified
Interpretation of results:
Category 2 (irritating to eyes) based on GHS criteria
Conclusions:
the test report concludes only minimal eye irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as eye irritant
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Justification for classification or non-classification