Registration Dossier

Administrative data

First-aid measures

1. Description of first aid measures
General notes
Do not leave affected person unattended. Remove victim out of the danger area. Keep affected person warm, still and covered.
Take off immediately all contaminated clothing. In all cases of doubt, or when symptoms persist, seek medical advice. In case
of unconsciousness place person in the recovery position. Never give anything by mouth.
Following inhalation
If breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. Provide fresh air.
Following skin contact
Wash with plenty of soap and water.


Following eye contact
Remove contact lenses, if present and easy to do. Continue rinsing. Irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.
Following ingestion
Rinse mouth with water (only if the person is conscious). Do NOT induce vomiting.

2. Most important symptoms and effects, both acute and delayed
Symptoms and effects are not known to date.

3. Indication of any immediate medical attention and special treatment needed
none

Fire-fighting measures

1. Extinguishing media
Suitable extinguishing media
Dry extinguishing powder, Carbon dioxide (CO2), Sand
Unsuitable extinguishing media
Water, Foam

2. Special hazards arising from the substance or mixture
In case of insufficient ventilation and/or in use, may form flammable/explosive vapour-air mixture. Solvent vapours are heavier
than air and may spread along floors. Places which are not ventilated, e.g. unventilated below ground level areas such as
trenches, conduits and shafts, are particularly prone to the presence of flammable substances or mixtures.
Hazardous combustion products
Nitrous gases, Hydrogen cyanide (HCN, prussic acid), Carbon monoxide (CO), Carbon dioxide (CO2), Siliconoxides

3. Advice for firefighters
Keep containers cool with water spray. In case of fire and/or explosion do not breathe fumes. Co-ordinate firefighting measures
to the fire surroundings. Do not allow firefighting water to enter drains or water courses. Collect contaminated firefighting water
separately. Fight fire with normal precautions from a reasonable distance. Precipitate combustion gases with water spray if possible.

Accidental release measures

1. Personal precautions, protective equipment and emergency procedures
For non-emergency personnel
Remove persons to safety.
For emergency responders
Wear breathing apparatus if exposed to vapours/dust/spray/gases.

2. Environmental precautions
Keep away from drains, surface and ground water. Retain contaminated washing water and dispose of it. If substance has
entered a water course or sewer, inform the responsible authority.

3. Methods and material for containment and cleaning up
Advices on how to contain a spill
Covering of drains
Advices on how to clean up a spill
Wipe up with absorbent material (e.g. cloth, fleece). Collect spillage: sawdust, kieselgur (diatomite), sand, universal binder
Appropriate containment techniques
Use of adsorbent materials.
Other information relating to spills and releases
Place in appropriate containers for disposal. Ventilate affected area.

4. Reference to other sections: Hazardous combustion products: see section "Firefighting measures". Personal protective equipment: see section "Exposure controls/personal protection". Incompatible materials: see section "Stability and reactivity". Disposal considerations: see section "Disposal considerations".

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediates. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site. Written confirmation of application of Strictly Controlled Conditions has been received from affected Distributor and Downstream Manufacturer/User of the Registrant's intermediate.

1. Precautions for safe handling
Recommendations
- measures to prevent fire as well as aerosol and dust generation
Use local and general ventilation. Avoidance of ignition sources. Keep away from sources of ignition - No smoking. Take precautionary
measures against static discharge. Use only in well-ventilated areas. Due to danger of explosion, prevent leakage of
vapours into cellars, flues and ditches. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/
lighting/equipment. Use only non-sparking tools.
- specific notes/details
Places which are not ventilated, e.g. unventilated below ground level areas such as trenches, conduits and shafts, are particularly
prone to the presence of flammable substances or mixtures. Vapours are heavier than air, spread along floors and form explosive
mixtures with air. Vapours may form explosive mixtures with air.
Advice on general occupational hygiene
Wash hands after use. Do not eat, drink and smoke in work areas. Remove contaminated clothing and protective equipment before
entering eating areas. Never keep food or drink in the vicinity of chemicals. Never place chemicals in containers that are
normally used for food or drink. Keep away from food, drink and animal feedingstuffs.

2. Conditions for safe storage, including any incompatibilities
Managing of associated risks
- explosive atmospheres
Keep container tightly closed and in a well-ventilated place. Use local and general ventilation. Keep cool. Protect from sunlight.
- flammability hazards
Keep away from sources of ignition - No smoking. Keep away from heat, hot surfaces, sparks, open flames and other ignition
sources. No smoking. Take precautionary measures against static discharge. Protect from sunlight.
Control of effects
Protect from moisture.
- ventilation requirements
Keep any substance that emits harmful vapours or gases in a place that allows these to be permanently extracted. Use local and
general ventilation. Ground/bond container and receiving equipment.
- packaging compatibilities
Only packagings which are approved (e.g. acc. to ADR) may be used.

3. Specific end use(s)
No information available.

Transport information

Land transport (ADR/RID)

UN number:
3383
Proper shipping name and description:
TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S.
Chemical name:
Trimethylsilyl cyanide
Language:
English
Class:
6.1
Classification code:
TF1
Packaging group:
I
Labels:
6.1+3, fish and tree
Special Provisions:
274, 802(ADN)
Remarks:
Environmental Hazards: yes (hazardous to the aquatic environment)
Excepted quantities (EQ): E0
Limited quantities (LQ): 0
Transport category (TC): 1
Tunnel restriction code (TRC): C/D
Hazard identification No: 663
Emergency Action Code: 3WE

Inland waterway transport (ADN(R))

UN number:
3383
Proper shipping name and description:
TOXIC BY INHALATION LIQUID, FLAMMABLE,
N.O.S.
Chemical name:
Trimethylsilyl cyanide
Language:
English
Class:
6.1
Classification code:
TF1
Packaging group:
I
Labels:
6.1+3, fish and tree
Remarks
Environmental Hazards: yes (hazardous to the aquatic environment)
Special provisions (SP): 274, 802(ADN)
Excepted quantities (EQ): E0
Limited quantities (LQ): 0
Transport category (TC): 1
Tunnel restriction code (TRC): C/D
Hazard identification No: 663
Emergency Action Code: 3WE

Marine transport (IMDG)

UN number:
3383
Proper shipping name and description:
TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S.
Chemical name:
Trimethylsilyl cyanide
Class:
6.1
Packaging group:
I
EmS code:
F-E, S-D
Labels:
6.1+3, fish and tree
Marine pollutant
Remarksopen allclose all
Special provisions (SP): 274
Excepted quantities (EQ): E0
Limited quantities (LQ): 0
Stowage category: D
Segregation Group: 6 - Cyanides
Subsidiary risk(s) 3
Marine pollutant = true

Air transport ICAO/IATA

UN number:
3383
Proper shipping name and description:
Toxic by inhalation liquid, flammable, n.o.s.
Chemical name:
Trimethylsilyl cyanide
Class:
6.1
Packaging group:
I
Remarks
Environmental Hazards: yes (hazardous to the aquatic environment)
ERG Code: 6F
Subsidiary risk(s) 3

Additional transport information

Additional transport information
Environmental hazards: hazardous to the aquatic environment

Special precautions for user: Provisions for dangerous goods (ADR) should be complied within the premises.
Transport in bulk according to Annex II of MARPOL and the IBC Code: The cargo is not intended to be carried in bulk.
Subsidiary risk(s): 3 (flammable liquid)

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediates. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site. Written confirmation of application of Strictly Controlled Conditions has been received from affected Distributor and Downstream Manufacturer/User of the Registrant's intermediate.

1. Control Parameters
No Information available

2. Exposure controls
Appropriate engineering controls
Local and general ventilation.
Individual protection measures (personal protective equipment)
Eye/face protection
Splash goggles.
Skin protection
- hand protection
Wear suitable gloves. Chemical protection gloves are suitable, which are tested according to EN 374. Check leak-tightness/impermeability
prior to use. In the case of wanting to use the gloves again, clean them before taking off and air them well. For special
purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with
the supplier of these gloves.
- type of material IIR: isobutene-isoprene (butyl) rubber
- breakthrough times of the glove material >480 minutes
- other protection measures
For special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together
with the supplier of these gloves. In the case of wanting to use the gloves again, clean them before taking off and air them
well.
Take recovery periods for skin regeneration. Preventive skin protection (barrier creams/ointments) is recommended. Wash
hands thoroughly after handling. Suitable protective clothing.
Respiratory protection
In exceptional situations Wear respiratory protection. Have suitable respiratory equipment ready or carry with you.
Environmental exposure controls
Use appropriate container to avoid environmental contamination. Keep away from drains, surface and ground water.

Stability and reactivity

1.Reactivity
Concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials". It's a reactive substance. Risk of ignition.
If heated:
Risk of ignition

2. Chemical stability
See below "Conditions to avoid".

3. Possibility of hazardous reactions
Dangerous/dangerous reactions with: Water ( -> Hydrogen cyanide (HCN, prussic acid))

4. Conditions to avoid
Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Protect from moisture.
Hints to prevent fire or explosion
Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools. Take precautionary measures
against static discharge.

5. Incompatible materials
Water, protic substances, Bases, Oxidisers
Release of toxic materials with:
Water

6. Hazardous decomposition products
Hydrogen cyanide (HCN, prussic acid). Hazardous combustion products: see section "fire-fighting measures"

Disposal considerations

Waste treatment methods
Waste treatment-relevant information
Dispose of contents/container in accordance with local/regional/national/international regulations.
Sewage disposal-relevant information
Do not empty into drains. Avoid release to the environment. Refer to special instructions/safety data sheets.
Waste treatment of containers/packagings
It is a dangerous waste; only packagings which are approved (e.g. acc. to ADR) may be used. Completely emptied packages
can be recycled. Handle contaminated packages in the same way as the substance itself.
Remarks
Please consider the relevant national or regional provisions. Waste shall be separated into the categories that can be handled
separately by the local or national waste management facilities.