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Adsorption / desorption

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Description of key information

Key value for chemical safety assessment

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ADONA is an ionisable substance which will dissociate in water, forming ammonium (cation) and DONA (anion). Koc of the DONA anion was assessed by HPLC (OECD Guideline 121), using a single, isocratic mobile phase buffered at pH 7.1. DONA has a pKa of 1.8 (in 1:1 water:acetonitrile) and will remain in anionic form at all environmentally relevant pH values 1 . Therefore, the HPLC results are generally applicable and provide information on DONA anion sorption. DONA anion eluted before the least-retained reference compound (acetanilide, log Koc 1.25) and was assigned an upper limit log Koc ≤1.3. ADONA has a low potential for adsorption and further testing is not necessary.

1 A summary of the DONA pKa study can be found in the information included with REACH registration of DONA; REACH Registration number 01-2119991106-35-0000 (10 July 2013)

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