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Hydrolysis

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Description of key information

The test substance ammonium 2,2,3-trifluoro-3-[1,1,2,2,3,3-hexafluoro-3-(trifluoromethoxy)-propoxy]propanoate (ADONA) had a hydrolysis half life  > 1 year based on test conducted under OECD Guideline 111 (Hydrolysis as a Function of pH).

Key value for chemical safety assessment

Additional information

Hydrolysis of ADONA was conducted in pH 4, 7 and 9 buffers and at 50 ± 0.5 °C for up to 5 days. Concentrations of ADONA at the initial and the end of hydrolysis experiment were measured by HPLC. Hydrolysis rate were determined by % decomposition of the test material. The % decomposition of ADONA at pH 4, pH 7 and pH 9 ranged from 0 to 1.12% after 2.4 hours and 5 days at 50°C, the hydrolysis half life is reported as > 1 year. The test substance is considered hydrolytically stable.

This is a guideline study conducted under GLP. Therefore, it is considered to be reliable with acceptable restriction.