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Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
16 July – 03 October, 1996
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted according to OECD and EU and in accordance with GLP. Study material is well characterized.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report date:
1997

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Version / remarks:
Paris, 1981
Qualifier:
according to guideline
Guideline:
other: OJEC L383 A/15-21 Siwoloboff method
GLP compliance:
yes
Type of method:
method according to Siwoloboff

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
424-660-8
EC Name:
-
Cas Number:
224631-15-6
Molecular formula:
Hill formula: C18H26N4O5S CAS formula: C18H26N4O5S
IUPAC Name:
(S)-2,5-dioxopyrrolidin-1-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate

Results and discussion

Boiling point
Atm. press.:
ca. 1 atm
Decomposition:
yes
Remarks:
from clear liquid to dark brown liquid
Decomp. temp.:
>= 153 - <= 192 °C
Remarks on result:
other: On cooling the sample set as a hard brown solid

Applicant's summary and conclusion

Conclusions:
Liquified A-133816 decomposes from a clear colourless liquid to a dark brown liquid over a temperature range of 153°C to 192°C.
Complete liquefaction at 115°C for Sample 1 and 117°C for Sample 2.

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