Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
toxicity to aquatic algae and cyanobacteria
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Reason / purpose:
data waiving: supporting information
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
according to
Guideline:
other: not specified
Principles of method if other than guideline:
not specified
GLP compliance:
not specified
Analytical monitoring:
no
Test organisms (species):
Scenedesmus quadricauda
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
7 d
Key result
Duration:
48 h
Dose descriptor:
other: Toxicity threshold
Effect conc.:
ca. 1 800 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: mean extinction value
Validity criteria fulfilled:
yes

Description of key information

Key value for chemical safety assessment

EC50 for freshwater algae:
1 800 mg/L

Additional information

No studies were conducted on the target substance. The target substance is hydrolytically unstable that, when coming into contact with water, it rapidly hydrolyzs to form 2-propanol, isostearic aicd and insoluble titanium dioxide. Therefore, the intrinsic toxicity of the target substance lies in the hydrolysis products.

The titanium dioxide is not considered further in this report as aquatic toxicity assessments do not apply.

Isostearic acid has very low water solubility (c.a. 0.597 mg/l at 20°C) and therefore exposure to the isostearic acid is unlikely.

2-propanol is practically miscible with water and therefore is taken into consideration. The toxicity threshold to Scenedesmus quadricauda was >1800 mg/l (Bringmann and Kühn, 1980). This value is used for CSA evaluation.