Tris(isooctadecanoato-O)(propan-2-olato)titanium

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

toxicity to aquatic algae and cyanobacteria

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Reason / purpose for cross-reference:

data waiving: supporting information

Reference 2

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Qualifier:

according to guideline

Guideline:

other: not specified

Principles of method if other than guideline:

not specified

GLP compliance:

not specified

Analytical monitoring:

no

Test organisms (species):

Scenedesmus quadricauda

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

7 d

Key result

Duration:

48 h

Dose descriptor:

other: Toxicity threshold

Effect conc.:

ca. 1 800 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: mean extinction value

Validity criteria fulfilled:

yes

Key value for chemical safety assessment

EC50 for freshwater algae:

1 800 mg/L

Additional information

No studies were conducted on the target substance. The target substance is hydrolytically unstable that, when coming into contact with water, it rapidly hydrolyzs to form 2-propanol, isostearic aicd and insoluble titanium dioxide. Therefore, the intrinsic toxicity of the target substance lies in the hydrolysis products.

The titanium dioxide is not considered further in this report as aquatic toxicity assessments do not apply.

Isostearic acid has very low water solubility (c.a. 0.597 mg/l at 20°C) and therefore exposure to the isostearic acid is unlikely.

2-propanol is practically miscible with water and therefore is taken into consideration. The toxicity threshold to Scenedesmus quadricauda was >1800 mg/l (Bringmann and Kühn, 1980). This value is used for CSA evaluation.