Registration Dossier

Administrative data

Endpoint:
basic toxicokinetics in vitro / ex vivo
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Objective of study:
other: Assessment of toxicokinetic behaviour
Test guideline
Qualifier:
according to
Guideline:
other: Assessment of degradation products
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Metabolite characterisation studies

Metabolites identified:
no

Any other information on results incl. tables

Testing has been performed to confirm the degradation of the substance in diluted solutions in water and it is confirmed that in common with the range of organo-titanium complexes of this nature, there will be rapid degradation (30 minutes) with reversion back to starting materials.

 

These abiotic degradation products have been identified as:

 

Propan-2-ol

triisopropanolamine

Propylene glycol

Ethylene glycol

Applicant's summary and conclusion