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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
Deviations:
no
GLP compliance:
yes
Test material information:
Composition 1
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
freshwater
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 4 050 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
not applicable
Conclusions:
The substance and its degradation products are not considered hazardous to Daphnia
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Justification for type of information:
Read across valid as the substnace tested is also titanate complex with glycol and alkylamine, degrading in water to similar degradation products.
Reason / purpose:
read-across source
Related information:
Composition 1
Reference:
Composition 0
Qualifier:
according to
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
Deviations:
no
GLP compliance:
yes
Test material information:
Composition 1
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
freshwater
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 4 050 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
not applicable
Conclusions:
The substance and its degradation products are not considered hazardous to Daphnia

Description of key information

Figure cited is for risk assessment purposes, but no effects seen at maximum tested concentrations in different studies

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
200 mg/L

Additional information

This figure has not been used to set the PNEC. The PNEC is based on the Daphnia reproduction study for triethanolamine.

Supporting data on another titanate suggest low toxicity (> 4000 mg/l)