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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(butan-2-yl)-4-{4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
EC Number:
607-685-0
Cas Number:
252964-68-4
Molecular formula:
C23H29N5O2
IUPAC Name:
1-(butan-2-yl)-4-{4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
Details on test material:
no data

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
methanol
Solubility:
1.8 g/L
Remarks on result:
other: room temperature
Medium:
ethanol
Solubility:
1.2 g/L
Remarks on result:
other: room temperature
Medium:
isopropanol
Solubility:
0.57 g/L
Remarks on result:
other: room temperature
Medium:
other: dichloromethane
Solubility:
210 g/L
Remarks on result:
other: room temperature
Medium:
other: 2-propanone
Solubility:
6.5 g/L
Remarks on result:
other: room temperature
Details on results:
no data

Any other information on results incl. tables

Table 1 Solubility of the T001329 for 24 hours

 Solvent  Concentration in g/L solution

Solubility at 20 °C (Condition 10)

 methanol  2.3
 ethanol 1.7
 2 -propanol 1.2
 dichloromethane  210
 2 -propanone  6.8
 ethyl acetate  5.6
 methylbenzene  6.2
 N,N-dimethylformamide 31
 4 -methyl-2 -pentanone  3.9
 2 -butanone  10
 1 -methoxy-2 -propanol  7.5
 N,N-dimethylacetamide  46
 acetic acid  180
 tetrahydrofuran  28

Applicant's summary and conclusion