Registration Dossier
Registration Dossier
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EC number: 205-009-5 | CAS number: 131-08-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
A valid Ames test according to OECD guideline 471 is available. The study was performed to investigate the potential of Anthrachinon-2-sulfonsäure, Na-Salz Monohydrat CAS 153277-35-1 to induce gene mutations according to the plate incorporation test (experiment I) and the pre-incubation test (experiment II) using the Salmonella typhimurium strains TA 1535, TA 1537, TA 98, TA 100, and the Escherichia coli strain WP2 uvrA. The assay was performed in two independent experiments both with and without liver microsomal activation.
Anthrachinon-2-sulfonsäure, Na-Salz Monohydrat CAS 153277-35-1 is considered to be non-mutagenic (negative) in this Salmonella typhimurium and Escherichia coli reverse mutation
assay.
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
In a valid Ames test according to guideline 471 Anthrachinon-2-sulfonsäure, Na-Salz Monohydrat CAS 153277-35-1 was negative.
According to CLP classification criteria (Regulation (EC) No 1272/2008) a classification is therefore not justified.
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