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EC number: 276-380-9
CAS number: 72140-65-9
MTDID 15670 was administered to five Wistar rats of each sex by a single
dermal application at 2000 mg/kg body weight for 24 hours. Animals were
subjected to daily observations and weekly determination of body weight.
Macroscopic examination was performed after terminal sacrifice (Day 15).
No mortality occurred. Chromodacryorrhoea and/or ptosis were noted for
most animals on Day 1. The changes noted in body weight gain in males
and females were within the range expected for rats used in this type of
study and were therefore considered not indicative of toxicity. No
abnormalities were found at macroscopic post mortem examination of the
animals. Based on the results of the study, the dermal LD50 in rats was
> 2000 mg/kg bw for MTDID 15670.
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