Registration Dossier
Registration Dossier
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EC number: 211-779-3 | CAS number: 695-12-5
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-06-12 to 2017-08-24
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- 15 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- 37 d
- Temp.:
- 20 °C
- pH:
- ca. 5
- Details on results:
- The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C. The examined pH values are approx. 5 in all sample solutions.
- Conclusions:
- The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C and pH 5. The water solubility was determined according to OECD Guideline 105.
- Executive summary:
The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C and pH 5. The water solubility was determined according to OECD Guideline 105.
Reference
An overview of sampling dates of flask 1, the determined sample content as well as the corresponding deviations are summarised in table 1.
Table 1: Sampling and determined sample content of flask 1
sampling date |
test duration [d] |
determined sample content [mg/L] |
deviation from the previous measurement [%] |
2017-07-04 |
22 |
15 |
- |
2017-07-05 |
23 |
17 |
+12 |
2017-07-07 |
25 |
17 |
+3 |
2017-10-07 |
28 |
18 |
+4 |
|
mean (n=4) |
17 |
|
SD |
1,3 |
||
RSD [%] |
7,9 |
Agitation of all flasks was stopped after 37 days as the last three control points differed no more than 15 % and showed no significant upward tendency.
Final examination of flasks 2 to 5 was conducted on 19. Jul. 2017 after 24 hours of temperature equilibration (20 °C ± 0.5 °C). The examined data from TC measurements are given in table 2 together with the weigh-in of each sample and the measured pH values.
Table 2: Final examination of flasks 2 to 5
flask no. |
weigh-in [g] |
volume (water) [mL] |
pH (approx.) [-] |
calculated water solubility [mg/L] |
2 |
1,9190 |
75 |
5 |
13 |
3 |
1,9270 |
75 |
5 |
14 |
4 |
1,9331 |
75 |
5 |
18 |
5 |
- |
75 |
5 |
≤ 1 |
|
mean (n=6) |
15 |
||
SD |
2,3 |
|||
RSD [%] |
15,1 |
|||
Description of key information
The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C and pH 5. The water solubility was determined according to OECD Guideline 105.
Key value for chemical safety assessment
- Water solubility:
- 15 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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